Does Soy foods Affect Pregnenolone?

Amount or timing may matter

The short answer

Pregnenolone is a precursor to all steroid hormones. Soy isoflavones may influence downstream conversion by competing at estrogen receptors.

How to arrange timing

Consult a healthcare provider about soy intake when supplementing with pregnenolone.

Reference

Reference noted for this food and supplement combination: Examine.com; Weber et al., Clin Pharmacol Ther 1999

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.