Does Grapefruit Affect Saw Palmetto?

May affect absorption or how you feel

The short answer

Saw palmetto fatty acids may be partly metabolized by CYP3A4. Grapefruit could modestly increase its bioavailability.

How to arrange timing

Separate saw palmetto from grapefruit by 2 hours as a precaution.

Reference

Reference noted for this food and supplement combination: Examine.com

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.