Does Grapefruit Affect Resveratrol?

May affect absorption or how you feel

The short answer

Grapefruit inhibits CYP3A4, which may increase resveratrol bioavailability but also increase risk of side effects.

How to arrange timing

Monitor for side effects if consuming grapefruit with resveratrol.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.