Does Grapefruit Affect Boswellia?

Amount or timing may matter

The short answer

Boswellic acids are CYP3A4 substrates. Grapefruit may increase their blood levels and potentiate anti-inflammatory but also GI side effects.

How to arrange timing

Separate boswellia from grapefruit by at least 4 hours.

Reference

Reference noted for this food and supplement combination: Examine.com; Kruger et al., Planta Med 2009

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.