Does Grapefruit Affect Bacopa Monnieri?

May affect absorption or how you feel

The short answer

Bacosides are partially metabolized by CYP3A4. Grapefruit may modestly increase bacopa blood levels.

How to arrange timing

Separate bacopa from grapefruit by 2 hours as a precaution.

Reference

Reference noted for this food and supplement combination: Examine.com; Ramasamy et al., J Ethnopharmacol 2014

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.