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Does Grapefruit Affect Alpha-Lipoic Acid?
May affect absorption or how you feel
The short answer
Alpha-lipoic acid is partially metabolized by CYP enzymes. Grapefruit may modestly increase its blood levels and hypoglycemic effect.
How to arrange timing
Separate ALA from grapefruit by 2 hours, especially if managing blood sugar.
Reference
Reference noted for this food and supplement combination: Examine.com
Important context
The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.