Does Dairy Affect Fisetin?

May affect absorption or how you feel

The short answer

Milk proteins bind polyphenols like fisetin through hydrophobic and hydrogen bonding, reducing their absorption.

How to arrange timing

Take fisetin at least 1 hour apart from dairy.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.