Does Caffeine Affect Vitamin B6?

May affect absorption or how you feel

The short answer

Caffeine may interfere with B6 absorption and increase its metabolic demand.

How to arrange timing

Take B6 at least 1 hour apart from caffeinated drinks.

Reference

Reference noted for this food and supplement combination: NIH ODS 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.