Does Caffeine Affect Vitamin B12?

May affect absorption or how you feel

The short answer

Caffeine may reduce B12 absorption in the stomach by altering gastric acid.

How to arrange timing

Take B12 at least 1 hour apart from coffee.

Reference

Reference noted for this food and supplement combination: NIH ODS 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.