Does Caffeine Affect Manganese?

May affect absorption or how you feel

The short answer

Coffee polyphenols and tannins chelate manganese in the gut, reducing its absorption similar to other divalent minerals.

How to arrange timing

Take manganese supplements at least 2 hours apart from coffee.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.