Does Caffeine Affect CoQ10?

May affect absorption or how you feel

The short answer

Caffeine may increase CoQ10 metabolism via CYP enzyme induction, potentially reducing its bioavailability.

How to arrange timing

Separate CoQ10 from caffeine by at least 1 hour.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.