Does Caffeine Affect Biotin?

May affect absorption or how you feel

The short answer

Caffeine's diuretic properties increase renal clearance of water-soluble biotin.

How to arrange timing

Take biotin at least 1 hour apart from caffeinated drinks.

Reference

Reference noted for this food and supplement combination: NIH ODS 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.