Does Alcohol Affect Magnolia Bark?

Use extra care with this combination

The short answer

Magnolia bark's honokiol is a GABA-A receptor modulator. Combined with alcohol, it may cause dangerous CNS depression.

How to arrange timing

Avoid alcohol within 6 hours of taking magnolia bark extract.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.