Does Alcohol Affect Kratom?

Use extra care with this combination

The short answer

Both kratom and alcohol are CNS depressants with hepatotoxic potential. Combined use risks respiratory depression, excessive sedation, and liver failure.

How to arrange timing

Never combine kratom with alcohol. Life-threatening interaction.

Reference

Reference noted for this food and supplement combination: FDA Safety Warning 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.