Does Alcohol Affect Black Cohosh?

Use extra care with this combination

The short answer

Black cohosh has known hepatotoxic potential. Combining with alcohol significantly increases liver damage risk.

How to arrange timing

Avoid alcohol when taking black cohosh supplements.

Reference

Reference noted for this food and supplement combination: FDA; NIH NCCIH 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.